Down-Regulation of Tumoricidal NK and NK

نویسندگان

  • Masahiro Takigawa
  • Naohiro Seo
  • Yoshiki Tokura
  • Fukumi Furukawa
چکیده

Lesions Coinfiltrating in Early B16 Melanoma T Cells β α T and δ γ Expressed on Th2-Type Molecules b T Cell Activities by MHC K

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Microenvironment and Immunology IL-15 and Type I Interferon Are Required for Activation of Tumoricidal NK Cells by Virus-Infected Dendritic Cells

There is increasing evidence that natural killer (NK) cells play an important role in antitumor immunity following dendritic cell (DC) vaccination. Little is known, however, about the optimal stimulation of DCs that favors NK activation in tumor-bearing hosts. In this study, we demonstrate that treatment with toll-like receptor (TLR) ligands and infection with a mutant vesicular stomatitis viru...

متن کامل

IL-15 and type I interferon are required for activation of tumoricidal NK cells by virus-infected dendritic cells.

There is increasing evidence that natural killer (NK) cells play an important role in antitumor immunity following dendritic cell (DC) vaccination. Little is known, however, about the optimal stimulation of DCs that favors NK activation in tumor-bearing hosts. In this study, we demonstrate that treatment with toll-like receptor (TLR) ligands and infection with a mutant vesicular stomatitis viru...

متن کامل

Human Herpesvirus 8 (HHV8) Sequentially Shapes the NK Cell Repertoire during the Course of Asymptomatic Infection and Kaposi Sarcoma

The contribution of innate immunity to immunosurveillance of the oncogenic Human Herpes Virus 8 (HHV8) has not been studied in depth. We investigated NK cell phenotype and function in 70 HHV8-infected subjects, either asymptomatic carriers or having developed Kaposi's sarcoma (KS). Our results revealed substantial alterations of the NK cell receptor repertoire in healthy HHV8 carriers, with red...

متن کامل

نقش سلولهای کشنده طبیعی خون محیطی در سقط‌های مکرر خودبخود

Introduction: Recurrent spontaneous abortion (RSA) is defined as three or more consecutive miscarriages, which affects 0.8 to 1% of pregnant women. Despite several well-established etiologic factors, the cause of RSA cannot be determined in almost 60% of the cases. It has been postulated that a part of these repeated pregnancy losses might be due to immune causes. Material and Methods: In the ...

متن کامل

Human Papillomavirus and Cancer - Immunological Consequences of MHC Class I Down-Regulation

Few studies have been conducted on the causative factors associated with the development of cancer. Infection by high risk human papillomaviruses (HPVs) have been implicated as causative agents in a variety of cancers. HPV is capable of evading immune system and establishing persistent infections. Prolonged infection and lesion maintenance are associated with higher risk of neoplastic progressi...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 1998